Stay on the cutting edge with the newly revised eBook of Goldman?s Cecil Medicine, with over 400 updates personally selected by Dr. Lee Goldman and integrated directly into each chapter. Since 1927, Goldman?s Cecil Medicine has been the world?s most influential internal medicine resource and now in its 24th edition, continues to set the standard for all other references of its kind. Edited by Lee Goldman, MD and Andrew I. Schafer, MD, this is quite simply the fastest and best place to find all of the definitive, state-of-the-art clinical answers you needto understand, diagnosis, or treat essentially anything you are going to encounter. At your fingertips, you'll find authoritative, unbiased, evidence-based guidance on the evaluation and management of every medical condition from a veritable "Who's Who" of modern medicine.
Edited by Lee Goldman and Andrew I. Schafer
Part 1: Social and Ethical Issues in Medicine
1: Approach to Medicine, the Patient, and the Medical Profession: Medicine as a Learned and Humane Profession
Lee Goldman
Editor: Goldman, Lee
2: Bioethics in the Practice of Medicine
Ezekiel Emanuel
Editor: Goldman, Lee
3: Care of Dying Patients and Their Families
Robert Arnold
Editor: Goldman, Lee
4: Cultural Context of Medicine
Victoria M. Taylor
Editor: Goldman, Lee
5: Socioeconomic Issues in Medicine
Steven Schroeder
Editor: Goldman, Lee
Part 2: Principles of Evaluation and Management
6: Approach to the Patient: History and Physical Examination
David Simel
Editor: Goldman, Lee
7: Approach to the Patient with Abnormal Vital Signs
David L. Schriger
Editor: Goldman, Lee
8: Statistical Interpretation of Data
Thomas Newman;Charles McCulloch
Editor: Goldman, Lee
9: Using Data for Clinical Decisions
Thomas Lee
Editor: Goldman, Lee
10: Measuring Health and Health Care
Stephan D. Fihn
Editor: Goldman, Lee
11: Quality of Care and Safety of Patients
Robert Wachter
Editor: Goldman, Lee
12: Comprehensive Chronic Disease Management
Edward H. Wagner
Editor: Goldman, Lee
Part 3: Preventive and Environmental Issues
13: Counseling and Advising for Behavior Changes
F. Daniel Duffy
Editor: Goldman, Lee
14: The Periodic Health Examination
David Atkins
Editor: Goldman, Lee
15: Physical Activity
David M. Buchner
Editor: Goldman, Lee
16: Adolescent Medicine
Debra Katzman;Lawrence Neinstein
Editor: Goldman, Lee
17: Immunization
Walter Orenstein;William Atkinson
Editor: Goldman, Lee
18: Principles of Occupational and Environmental Medicine
Mark R. Cullen
Editor: Goldman, Lee
19: Radiation Injury
Arthur Upton
Editor: Goldman, Lee
20: Bioterrorism
John G. Bartlett
Editor: Goldman, Lee
21: Chronic Poisoning: Trace Metals and Others
Michael A McGuigan
Editor: Goldman, Lee
Part 4: Aging and Geriatric Medicine
22: Epidemiology of Aging: Implications of the Aging Society
Linda Fried
Editor: Goldman, Lee
23: Geriatric Assessment
David B. Reuben
Editor: Goldman, Lee
24: Common Clinical Sequelae of Aging
Kenneth Minaker
Editor: Goldman, Lee
25: Incontinence
Neil Resnick
Editor: Goldman, Lee
26: Neuropsychiatric Aspects of Aging
Sharon Inouye
Editor: Goldman, Lee
27: Delirium and Other Mental Status Problems in the Older Patient
Sharon Inouye
Editor: Goldman, Lee
Part 5: Clinical Pharmacology
28: Principles of Drug Therapy
Robert Diasio
Editor: Schafer, Andrew
29: Pain
Srinivasa N Raja;Steven P Cohen
Editor: Schafer, Andrew
30: Biology of Addiction
Steven E. Hyman
Editor: Schafer, Andrew
31: Nicotine and Tobacco
Tony P. George
Editor: Schafer, Andrew
32: Alcohol Abuse and Dependence
Patrick O'Connor
Editor: Schafer, Andrew
33: Drug Abuse and Dependence
Roger Weiss
Editor: Schafer, Andrew
34: Immunosuppressive Drugs, Including Corticosteroids
Grant Cannon
Editor: Schafer, Andrew
35: Biologic Agents
Cem Gabay
Editor: Schafer, Andrew
36: Prostaglandins, Aspirin, and Related Compounds
Carlo Patrono
Editor: Schafer, Andrew
37: Antithrombotic Therapy
Sam Schulman
Editor: Schafer, Andrew
38: Complementary and Alternative Medicine
Mary Charlson
Editor: Schafer, Andrew
Part 6: Genetics
39: Principles of Genetics
Bruce Korf
Editor: Schafer, Andrew
40: Single-Gene and Chromosome Disorders
James R. Lupski
Editor: Schafer, Andrew
41: The Inherited Basis of Common Diseases
David Altshuler
Editor: Schafer, Andrew
42: Applications of Molecular Technologies to Clinical Medicine
Geoffrey Ginsburg;Geoffrey Ginsburg
Editor: Schafer, Andrew
43: Gene and Cell Therapy
Karl Skorecki
Editor: Schafer, Andrew
Part 7: Principles of Immunology and Inflammation
44: The Innate and Adaptive Immune Systems
Cornelia Weyand;Jorg Goronzy
Editor: Schafer, Andrew
45: The Major Histocompatibility Complex
Peter K. Gregersen
Editor: Schafer, Andrew
46: Mechanisms of Immune-Mediated Tissue Injury
Jane Salmon
Editor: Schafer, Andrew
47: Mechanisms of Inflammation and Tissue Repair
Gary S. Firestein
Editor: Schafer, Andrew
48: Organ Transplantation
Megan Sykes
Editor: Schafer, Andrew
49: Complement in Health and Disease
David, R. Karp;V. Michael Holers
Editor: Schafer, Andrew
Part 8: Cardiovascular Disease
50: Approach to the Patient with Possible Cardiovascular Disease
Lee Goldman
Editor: Goldman, Lee
51: Epidemiology of Cardiovascular Disease
Michael Klag
Editor: Goldman, Lee
52: Cardiac Function and Circulatory Control
Andrew Marks
Editor: Goldman, Lee
53: Radiology of the Heart
Murray G. Baron;Arthur E. Stillman
Editor: Goldman, Lee
54: Electrocardiography
Leonard I Ganz
Editor: Goldman, Lee
55: Echocardiography
Catherine Otto
Editor: Goldman, Lee
56: Non-invasive Cardiac Imaging
Christopher Kramer
Editor: Goldman, Lee
57: Catheterization and Angiography
Morton Kern
Editor: Goldman, Lee
58: Heart Failure: Pathophysiology and Diagnosis
Barry Massie
Editor: Goldman, Lee
59: Heart Failure: Management and Prognosis
John JV McMurray;Marc A. Pfeffer
Editor: Goldman, Lee
60: Diseases of the Myocardium and Endocardium
William McKenna;Perry Elliott
Editor: Goldman, Lee
61: Principles of Electrophysiology
Hugh Calkins
Editor: Goldman, Lee
62: Approach to the Patient with Suspected Arrhythmia
Jeffrey Olgin
Editor: Goldman, Lee
63: Approach to Cardiac Arrest and Life-Threatening Arrhythmias
Robert Myerburg
Editor: Goldman, Lee
64: Cardiac Arrhythmias with Supraventricular Origin
Peter Zimetbaum
Editor: Goldman, Lee
65: Ventricular Arrhythmias
William Stevenson
Editor: Goldman, Lee
66: Electrophysiologic Interventional Procedures and Surgery
Fred Morady
Editor: Goldman, Lee
67: Arterial Hypertension
Ronald Victor
Editor: Goldman, Lee
68: Pulmonary Hypertension
Valerie McLaughlin
Editor: Goldman, Lee
69: Congenital Heart Disease in Adults
Ariane Marelli
Editor: Goldman, Lee
70: Atherosclerosis, Thrombosis and Vascular Biology
Goran Hansson;Anders Hamsten
Editor: Goldman, Lee
71: Angina Pectoris
William Boden
Editor: Goldman, Lee
72: Acute Coronary Syndrome/Unstable Angina and Non-ST Elevation MI
Richard A. Lange
Editor: Goldman, Lee
73: ST-Elevation Myocardial Infarction and Complications of MI
Jeffrey Anderson
Editor: Goldman, Lee
74: Interventional and Surgical Treatment of Coronary Artery Disease
Paul Teirstein;Bruce Lytle
Editor: Goldman, Lee
75: Valvular Heart Disease
Blase Carabello
Editor: Goldman, Lee
76: Infective Endocarditis
Vance Fowler Jr.;Arnold Bayer
Editor: Goldman, Lee
77: Pericardial Disease
William Little;Jae K. Oh
Editor: Goldman, Lee
78: Diseases of the Aorta
Eric Isselbacher
Editor: Goldman, Lee
79: Atherosclerotic Peripheral Arterial Disease
Christopher White
Editor: Goldman, Lee
80: Other Peripheral Arterial Diseases
Jeffrey Olin
Editor: Goldman, Lee
81: Peripheral Venous Disease
Jeffrey Ginsberg
Editor: Goldman, Lee
82: Cardiac Transplantation
Mariell Jessup
Editor: Goldman, Lee
Part 9: Respiratory Diseases
83: Approach to the Patient with Respiratory Disease
Monica Kraft
Editor: Goldman, Lee
84: Imaging in Pulmonary Disease
Paul Stark
Editor: Goldman, Lee
85: Respiratory Structure and Function: Mechanisms and Testing
Herbert Reynolds
Editor: Goldman, Lee
86: Disorders of Ventilatory Control
Atul Malhotra
Editor: Goldman, Lee
87: Asthma
Jeffrey Drazen
Editor: Goldman, Lee
88: COPD
Dennis Niewoehner
Editor: Goldman, Lee
89: Cystic Fibrosis
Frank Accurso
Editor: Goldman, Lee
90: Bronchiectasis, Atelectasis, Cysts, and Localized Lung Disorders
Anne O'Donnell
Editor: Goldman, Lee
91: Alveolar Filling Disorders
Stephanie, M. Levine
Editor: Goldman, Lee
92: Interstitial Lung Disease
Ganesh Raghu
Editor: Goldman, Lee
93: Occupational Pulmonary Disorders
Susan Tarlo
Editor: Goldman, Lee
94: Physical and Chemical Injuries of the Lung
David C. Christiani
Editor: Goldman, Lee
95: Sarcoidosis
Michael Iannuzzi
Editor: Goldman, Lee
96: Acute Bronchitis and Tracheitis
Richard. P. Wenzel
Editor: Goldman, Lee
97: Overview of Pneumonia
Andrew H. Limper
Editor: Goldman, Lee
98: Pulmonary Embolism
Jeffrey Weitz
Editor: Goldman, Lee
99: Diseases of the Diaphragm, Chest Wall, Pleura, and Mediastinum
F. Dennis McCool
Editor: Goldman, Lee
100: Obstructive Sleep Apnea/Hypopnea Syndrome
Robert C. Basner
Editor: Goldman, Lee
101: Interventional and Surgical Approaches to Lung Disease
Armin Ernst;Malcom DeCamp
Editor: Goldman, Lee
Part 10: Critical Care Medicine
102: Approach to the Patient in a Critical Care Setting
Deborah J. Cook
Editor: Goldman, Lee
103: Respiratory Monitoring in Critical Care
James Stoller;Nicholas S. Hill
Editor: Goldman, Lee
104: Acute Respiratory Failure
Leonard Hudson;Arthur Slutsky
Editor: Goldman, Lee
105: Mechanical Ventilation
Leonard Hudson;Arthur Slutsky
Editor: Goldman, Lee
106: Approach to the Patient with Shock
Emanuel Rivers
Editor: Goldman, Lee
107: Cardiogenic Shock
Steven Hollenberg
Editor: Goldman, Lee
108: Shock Syndromes Related to Sepsis
James Russell
Editor: Goldman, Lee
109: Disorders Due to Heat and Cold
William Winkenwerder, Jr;Michael N Sawka
Editor: Goldman, Lee
110: Acute Poisoning
Marsha D. Ford I
Editor: Goldman, Lee
111: Electric Injury
Basil A. Pruitt Jr.
Editor: Goldman, Lee
112: Medical Aspects of Trauma and Burn Care
Robert H. Demling;Jonathan Gates;Reza Askari
Editor: Goldman, Lee
113: Venomous Snake Bites
Steven A. Seifert;James Armitage
Editor: Goldman, Lee
114: Venoms and Poisons from Marine Organisms
Jay Fox
Editor: Goldman, Lee
115: Rhabdomyolysis
Francis O'Connor;Patricia A. Deuster
Editor: Goldman, Lee
Part 11: Renal and Genitourinary Diseases
116: Approach to the Patient with Renal Disease
Donald Landry
Editor: Goldman, Lee
117: Structure and Function of the Kidneys
Qais Al-Awqati;Jonathan Barasch
Editor: Goldman, Lee
118: Disorders of Sodium and Water Homeostasis
Karl Skorecki;Denny Ausiello
Editor: Goldman, Lee
119: Potassium Disorders
Julian Seifter
Editor: Goldman, Lee
120: Acid-Base Disorders
Julian Seifter
Editor: Goldman, Lee
121: Disorders of Magnesium and Phosphorus
Alan S. L. Yu
Editor: Goldman, Lee
122: Acute Kidney Injury
Bruce Molitoris
Editor: Goldman, Lee
123: Glomerular Disorders and Nephrotic Syndromes
Gerald B. Appel;Jai Radhakrishnan
Editor: Goldman, Lee
124: Tubulointerstitial Diseases
Eric G Neilson
Editor: Goldman, Lee
125: Obstructive Uropathy
Mark Zeidel
Editor: Goldman, Lee
126: Diabetes and the Kidney
Raymond Harris
Editor: Goldman, Lee
127: Vascular Disorders of the Kidney
Thomas D. DuBose, Jr.
Editor: Goldman, Lee
128: Nephrolithiasis
Gary C Curhan
Editor: Goldman, Lee
129: Cystic Kidney Diseases
M. Amin Arnaout
Editor: Goldman, Lee
130: Hereditary Nephropathies and Abnormalities of the Urinary Tract
Lisa Guay-Woodford
Editor: Goldman, Lee
131: Benign Prostate Disease and Prostatitis
Michael Barry;Mary McNaughton-Collins
Editor: Goldman, Lee
132: Chronic Kidney Disease
William Mitch
Editor: Goldman, Lee
133: Treatment of Irreversible Renal Failure
Nina Tolkoff-Rubin
Editor: Goldman, Lee
Part 12:Gastrointestinal Diseases
134: Approach to the Patient with Gastrointestinal Disease
Kenneth McQuaid
Editor: Goldman, Lee
135: Diagnostic Imaging Procedures in Gastroenterology
Perry J Pickhardt
Editor: Goldman, Lee
136: Gastrointestinal Endoscopy
P. Jay Pasricha
Editor: Goldman, Lee
137: Gastrointestinal Hemorrhage and Occult Gastrointestinal Bleeding
Dennis M. Jensen
Editor: Goldman, Lee
138: Disorders of Gastrointestinal Motility
Michael Camilleri
Editor: Goldman, Lee
139: Functional Gastrointestinal Disorders: Irritable Bowel Syndrome, Dyspepsia, and Noncardiac Chest Pain
Emeran Mayer
Editor: Goldman, Lee
140: Diseases of the Esophagus
David A. Katzka;Gary Falk
Editor: Goldman, Lee
141: Acid Peptic Disease
Ernst Kuipers;Martin Blaser
Editor: Goldman, Lee
142: Approach to the Patient with Diarrhea and Malabsorption
Carol E. Semrad
Editor: Goldman, Lee
143: Inflammatory Bowel Disease
Gary R. Lichtenstein
Editor: Goldman, Lee
144: Inflammatory and Anatomic Diseases of theINtestine, Peritoneum, Mesentery, and Omentum
Charlene Prather
Editor: Goldman, Lee
145: Vascular Diseases of the GI Tract
Stephen Hauser
Editor: Goldman, Lee
146: Pancreatitis
Chris E. Forsmark
Editor: Goldman, Lee
147: Diseases of the Rectum and Anus
Robert D. Madoff
Editor: Goldman, Lee
Part 13: Diseases of the Liver, Gallbladder, and Bile Ducts
148: Approach to the Patient with Liver Disease
Paul Martin
Editor: Goldman, Lee
149: Approach to the Patient with Jaundice or Abnormal Liver Test Results
Paul Berk;Kevin Korenblat
Editor: Goldman, Lee
150: Acute Viral Hepatitis
Jean-Michel Pawlotsky;Heiner Wedemeyer
Editor: Goldman, Lee
151: Chronic Viral Hepatitis
Jean-Michel Pawlotsky;John McHutchinson
Editor: Goldman, Lee
152: Toxin- and Drug-Induced Liver Disease
William Lee
Editor: Goldman, Lee
153: Inherited and Metabolic Hepatic Disorders
Bruce R Bacon
Editor: Goldman, Lee
154: Bacterial, Parasitic, Fungal, and Granulomatous Liver Diseases
Karen Krok;K. Rajender Reddy
Editor: Goldman, Lee
155: Alcoholic and NonAlcoholic Steatohepatitis
Naga P. Chalasani
Editor: Goldman, Lee
156: Cirrhosis and Its Sequelae
Guadalupe Garcia-Tsao
Editor: Goldman, Lee
157: Hepatic Failure and Liver Transplantation
Emmet Keeffe
Editor: Goldman, Lee
158: Diseases of the Gallbladder and Bile Ducts
Nezam H. Afdhal
Editor: Goldman, Lee
Part 14: Hematologic Diseases
159: Hematopoiesis and Hematopoietic Growth Factors
Kenneth Kaushansky
Editor: Schafer, Andrew
160: The Peripheral blood Smear
Barbara Bain
Editor: Schafer, Andrew
161: Approach to the Anemias
H. Franklin Bunn
Editor: Schafer, Andrew
162: Microcytic and Hypochromic Anemias
Gordon Ginder
Editor: Schafer, Andrew
163: Autoimmune and Intravascular Hemolytic Anemias
Robert Schwartz
Editor: Schafer, Andrew
164: Hemolytic Anemias: Red Cell Membrane and Metabolic Defects
Patrick Gallagher
Editor: Schafer, Andrew
165: Hemoglobinopathies: The Thalassemias
Maria Cappellini
Editor: Schafer, Andrew
166: Sickle Cell Disease and Associated Hemoglobinopathies
Martin