From the experts at Johns Hopkins University who bring you the bestselling Harriet Lane Handbook, the Harriet Lane Handbook of Pediatric Antimicrobial Therapy delivers quick, dependable answers to help you effectively treat a broad spectrum of pediatric infectious diseases. This highly regarded medical reference book is your pocket-sized source for all of the evidence-based recommendations you need to provide the best possible care to your young patients.
Notes and Abbreviations Used in Tables
1. Infectious Agents and Drugs of Choice
I. Recommended Treatment forBacterial Infections
II. Recommended Treatment forMycobacterial Infections
III. Recommended Treatment forViral Infections
IV. Recommended Treatment forFungal Infections
V. Recommended Treatment for Parasitic and Protozoal Infections
2. Recommended Empiric Antimicrobial Therapy for Selected Clinical Syndromes
3. Drug Dosing in Special Circumstances
4. Mechanisms of Action and Routes of Administration of Antimicrobial Agents
5. Mechanisms of Drug Resistance
I. Common Mechanisms of Microbial Resistance
II. Discordance Between in Vitro Susceptibility and in Vivo Efficacy
6. Therapeutic Drug Monitoring
I. General Principles
II. Antimicrobials Requiring Therapeutic Drug Monitoring
III. Special Topics in Antimicrobial Therapeutic Drug Monitoring
IV. Pharmacokinetic Monitoring in Therapeutic Drug Monitoring
V. Pharmacokinetic/Pharmacodynamic (PK/PD) Antimicrobial Relationships
VI. Drug Interactions
7. Adverse Drug Reactions
I. Blood
II. Cardiovascular
III. Central Nervous System
IV. Skin
V. Gastrointestinal
VI. Endocrine/METABOLIC
VII. Renal/Genitourinary
VIII. Respiratory
IX. Hepatic
X. Ocular
XI. Musculoskeletal
XII. Hypersensitivity
XIII. Other
8. Recommended Antimicrobial Prophylaxis for Selected Infectious Agents and Conditions
9. Antimicrobial Desensitization Protocols
I. Penicillin
II. Amoxicillin
III. Cephalosporins
IV. Trimethoprim/Sulfamethoxazole (TMP/SMX) Oral
V. Fluoroquinolone
VI. Vancomycin
VII. Aminoglycosides
VIII. Clindamycin
IX. Linezolid
X. Darunavir
10. Formulary