For 25 years, Rang and Dale?sPharmacology has delivered the core basic and clinical science information required by students and healthcare practitioners worldwide. Authors H. P. Rang, J. M. Ritter, R. J. Flower, and G. Henderson have ensured that the 8th Edition of this easy-to-read, comprehensive text continues the tradition of excellence with new coverage of drugs affecting the skin and new components online at studentconsult.com.
1. What is pharmacology?
2. How drugs act: general principles
3. How drugs act: molecular aspects
4. How drugs act: cellular aspects?excitation, contraction and secretion
5. Cell proliferation, apoptosis, repair and regeneration
6. Cellular mechanisms: host defence
7. Method and measurement in pharmacology
8. Absorption and distribution of drugs
9. Drug metabolism and elimination
10. Pharmacokinetics
11. Individual variation, pharmacogenetics and personalised medicine
Section 2: Chemical mediators
12. Chemical mediators and the autonomic nervous system
13. Cholinergic transmission
14. Noradrenergic transmission
15. 5-Hydroxytryptamine and the pharmacology of migraine
16. Purines
17. Local hormones 1: histamine and the biologically active lipids
18. Local hormones 2: peptides and proteins
19. Cannabinoids
20. Nitric oxide and related mediators
Section 3: Drugs affecting major organ systems
21. The heart
22. The vascular system
23. Atherosclerosis and lipoprotein metabolism
24. Haemostasis and thrombosis
25. Haemopoietic system and treatment of anaemia
26. Anti-inflammatory and immunosuppressant drugs
27. Skin
28. Respiratory system
29. The kidney and urinary system
30. The gastrointestinal tract
31. The control of blood glucose and drug treatment of diabetes mellitus
32. Obesity
33. The pituitary and the adrenal cortex
34. The thyroid
35. The reproductive system
36. Bone metabolism
Section 4: Nervous system
37. Chemical transmission and drug action in the central nervous system
38. Amino acid transmitters
39. Other transmitters and modulators
40. Neurodegenerative diseases
41. General anaesthetic agents
42. Analgesic drugs
43. Local anaesthetics and other drugs affecting sodium channels
44. Anxiolytic and hypnotic drugs
45. Antiepileptic drugs
46. Antipsychotic drugs
47. Antidepressant drugs
48. CNS stimulants and psychotomimetic drugs
49. Drug addiction, dependence and abuse
Section 5: Drugs used for the treatment of infections and cancer
50. Basic principles of antimicrobial chemotherapy
51. Antibacterial drugs
52. Antiviral drugs
53. Antifungal drugs
54. Antiprotozoal drugs
55. Anthelmintic drugs
56. Anticancer drugs
Section 6: Special topics
57. Harmful effects of drugs
58. Lifestyle drugs and drugs in sport
59. Biopharmaceuticals and gene therapy
60. Drug discovery and development
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