Pharmaceutics is one of the most diverse subject areas in all of pharmaceutical science. In brief, it is concerned with the scientific and technological aspects of the design and manufacture of dosage forms or medicines. An understanding of pharmaceutics is therefore vital for all pharmacists and those pharmaceutical scientists who are involved with converting a drug or a potential drug into a medicine that can be delivered safely, effectively and conveniently to the patient.
Now in its fourth edition, this best-selling textbook in pharmaceutics has been brought completely up to date to reflect the rapid advances in delivery methodologies by eye and injection, advances in drug formulations and delivery methods for special groups (such as children and the elderly), nanomedicine, and pharmacognosy. At the same time the editors have striven to maintain the accessibility of the text for students of pharmacy, preserving the balance between being a suitably pitched introductory text and a clear reflection of the state of the art.
New to this edition
New to this edition
1. Design of dosage forms?0
Peter York
PART 1: Scientific principles of dosage form design?
2. Dissolution and solubility?00
Michael E. Aulton
3. Properties of solutions?00
Michael E. Aulton
4. Surfaces and interfaces 00
Graham Buckton
5. Disperse systems?00
David Attwood
6. Rheology
Christopher Marriot
7. Kinetics?00
W. John Pugh
PART 2: Particle science and powder technology?00
8. Solid-state properties?00
Graham Buckton
9. Particle size analysis?00
J.N. Staniforth, Kevin M.G. Taylor
10. Particle size reduction and size separation?00
Michael E. Aulton, J.N. Staniforth
11. Mixing?00
Andrew M. Twitchell
12. Powder flow?00
Michael E. Aulton
PART 3: Pharmaceutical microbiology and sterilization?00
13. Fundamentals of microbiology?00
Geoffrey W. Hanlon
14. Pharmaceutical applications of microbiological techniques?00
Norman A. Hodges
15. Action of physical and chemical agents on microorganisms?00
Geoffrey W. Hanlon, Norman A. Hodges
16. Principles of sterilization?00
Susannah E. Walsh, Jean-Yves Maillard
17. Sterilization in practice?00
Jean-Yves. Maillard, Susannah E. Walsh
PART 4: Biopharmaceutical principles of drug delivery?000
18. Introduction to biopharmaceutics 000
Marianne Ashford
19. Gastrointestinal tract ? physiology and drug absorption?000
Marianne Ashford
20. Bioavailability ? physicochemical and dosage form factors?000
Marianne Ashford
21. Assessment of biopharmaceutical properties?000
Marianne Ashford
22. Dosage regimens?000
John H. Collett, Soraya Dhillon
PART 5: Dosage form design and manufacture?000
23. Pharmaceutical preformulation?000
Simon Gaisford
24. Solutions?000
Sudaxshina Murdan
25. Clarification?000
Andrew M. Twitchell
26. Suspensions 000
Susan A. Barker
27. Emulsions and Creams 000
Gillian M.Eccleston
28.Powders, granules and granulation 000
Michael E. Aulton, Malcolm P. Summers`
29. Drying?000
Michael E. Aulton
30. Tablets and compaction?000
Göran Alderborn
31. Modified-release oral drug delivery 000
Abdul W. Basit, Emma L. McConnell
32. Coating of tablets and multiparticulates?000
Stuart C. Porter
33. Hard capsules?000
Brian E. Jones
34. Soft capsules?000
Keith G. Hutchison, Josephine Ferdinando
35 Dissolution testing of solid dosage forms
Abdul W. Basit, Ana Cristina Freire
36 Parenteral drug delivery
Robert Lowe
37. Pulmonary drug delivery?000
Kevin M. G. Taylor
38. Nasal drug delivery?000
Gary P. Martin, Alison B. Lansley
39. Topical and transdermal drug delivery 000
Adrian C. Williams
40. Wound dressings?000
Gillian M. Eccleston
41. Ocular drug delivery 000
Hala Fadda, Ashkan Khalili, Peng T. Khaw, Steve Brocchini
42. Rectal and vaginal drug delivery?000
Joseph J. Tukker, Sanjay Garg
43. Design and administration of medicines for children and the elderly 000
Catherine Tuleu, David Wright
44. The formulation and manufacture of plant medicines 000
G. Brian Lockwood
45. Pharmaceutical nanotechnology and nanomedicines 000
Yvonne Perrie
46. Delivery of biopharmaceuticals 000
Ijeoma F. Uchegbu, A. G. Shätzlein
Part 6: PACKAGING AND STABILITY OF PHARMACEUTICAL PRODUCTS
47. Packaging 000
Sudaxshina Murdan
48. Chemical stability in dosage forms 000
Andrew R. Barnes
49. Product stability and stability testing 000
Michael E. Aulton
50. Microbial contamination, spoilage and preservation of medicines?000
Norman A. Hodges